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| Flybase description | The gene big brain is referred to in FlyBase by the symbol Dmel\bib (CG4722, FBgn0000180). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: cation channel activity. There is experimental evidence that it is involved in the biological process: endosomal lumen acidification; lateral inhibition; endosome organization; cell-cell adhesion; mesoderm development. 29 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; non-connected developing system; portion of tissue; somatic cell; multicellular structure; sense organ; sensillum; organ system subdivision; presumptive embryonic/larval nervous system; nervous system. It has one annotated transcript and one annotated polypeptide. Protein features are: Aquaporin; Aquaporin-like; Major intrinsic protein; Major intrinsic protein, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages. . |
