Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name esg
Flybase description The gene escargot is referred to in FlyBase by the symbol Dmel\esg (CG3758, FBgn0001981).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -40.6185 -2.5621 -3.442962 -1.7317 -3.813904 -1.7493 -37.61265 -3.794516
    Affimetrix absolute value 3.074 6.282 6.441 7.617 6.904 7.776 3.414 6.493
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 2 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: central nervous system development; germ-line stem cell maintenance; regulation of compound eye pigmentation; olfactory behavior; asymmetric neuroblast division; maintenance of imaginal histoblast diploidy; open tracheal system development; cell fate specification.
115 alleles are reported.
The phenotypes of these alleles are annotated with 32 unique terms, many of which group under: organ system subdivision; organ system; embryonic/larval dorsal branch; adult segment; external compound sense organ; embryonic/larval tracheal system; sensillum; somatic cell; imaginal precursor; hub cell; embryonic/larval dorsal branch 2; embryonic/larval dorsal branch 5; eo support cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages.
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