Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sv
Flybase description The gene shaven is referred to in FlyBase by the symbol Dmel\sv (CG11049, FBgn0005561).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -58.9806 -34.4638 -45.323956 -59.6838 -72.161421 -61.3409 -67.703 -52.673317
    Affimetrix absolute value 2.537 2.52 2.686 2.489 2.601 2.626 2.47 2.567
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: regulation of R7 cell differentiation; dendrite morphogenesis; neuron development; regulation of retinal cone cell fate specification; muscle organ development.
54 alleles are reported.
The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; adult segment; eo support cell; rhabdomere R7; rhabdomere; imaginal precursor; antennal segment; nervous system.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: Homeodomain-like; Paired box protein, N-terminal; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages.
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