Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name lat
Flybase description The gene latheo is referred to in FlyBase by the symbol Dmel\lat (CG4088, FBgn0005654).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -20.9611 -14.2745 -16.4208 -22.3936 -21.335388 -21.9081 -26.49614 -18.485197
    Affimetrix absolute value 4.07 3.792 4.164 3.914 4.384 4.123 3.841 4.045
    Affymetric present call in "x" number of chips 0 0 0 0 1 0 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: DNA binding.
There is experimental evidence that it is involved in the biological process: DNA-dependent DNA replication initiation.
38 alleles are reported.
The phenotypes of these alleles are annotated with: mushroom body; bouton; axon terminus; imaginal disc; embryonic/larval central nervous system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Origin recognition complex, subunit 3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.
This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.
The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.
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