Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Tom34
Flybase description This gene is referred to in FlyBase by the symbol Dmel\unc-45 (CG2708, FBgn0010812).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.8974 -2.0862 -2.946691 -3.5292 -4.217891 -2.5479 -5.25446 -3.851331
    Affimetrix absolute value 6.459 6.561 6.636 6.577 6.719 7.215 6.169 6.352
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding.
There is experimental evidence that it is involved in the biological process: chaperone-mediated protein folding; somatic muscle development; myosin filament assembly; cellular response to heat.
7 alleles are reported.
The phenotypes of these alleles are annotated with: myofibril; embryonic somatic muscle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Armadillo; Armadillo-like helical; Armadillo-type fold; Tetratricopeptide TPR-1; Tetratricopeptide repeat; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed during late pupal stages.
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