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Gene name | cpa | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene capping protein alpha is referred to in FlyBase by the symbol Dmel\cpa (CG10540, FBgn0034577). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: actin binding. There is experimental evidence that it is involved in the biological process: germarium-derived oocyte fate determination; wing disc development; regulation of lamellipodium assembly; actin cytoskeleton organization; negative regulation of actin filament polymerization; actin filament organization; negative regulation of filopodium assembly; phagocytosis, engulfment. 15 alleles are reported. The phenotypes of these alleles are annotated with: eye; wing disc; macrochaeta; wing hinge primordium; wing. It has one annotated transcript and one annotated polypeptide. Protein features are: F-actin capping protein, alpha subunit, conserved site; WASH complex, F-actin capping protein, alpha subunit. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed during early pupal stages. . |