Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name CG5976
Flybase description The gene iso Glutaminyl cyclase is referred to in FlyBase by the symbol Dmel\isoQC (CG5976, FBgn0036999).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.1906 -1.3334 -1.877778 -2.1043 -4.061495 -3.0027 -5.63577 -2.925005
    Affimetrix absolute value 6.356 7.228 7.347 7.317 6.8 6.987 6.061 6.744
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: glutaminyl-peptide cyclotransferase activity.
There is experimental evidence that it is involved in the biological process: peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase.
6 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Peptidase M28.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.
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