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|Flybase description||The gene aristaless is referred to in FlyBase by the symbol Dmel\al (CG3935, FBgn0000061).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: bristle development; antennal morphogenesis; positive regulation of Notch signaling pathway; leg disc development; imaginal disc-derived leg morphogenesis; elongation of arista core; negative regulation of transcription, DNA-dependent.
28 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: adult segment; organ system subdivision; adult mesothoracic segment; appendage segment; external compound sense organ; antennal segment; compound cell cluster organ; unguis; integumentary plate; mesothoracic preepisternum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-turn-helix motif, lambda-like repressor; Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Paired-like homeodomain protein, OAR.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 12-18 embryonic stages.