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|Flybase description||The gene β amyloid protein precursor-like is referred to in FlyBase by the symbol Dmel\Appl (CG7727, FBgn0000108).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: neuron projection morphogenesis; long-term memory; response to axon injury; peripheral nervous system development; synapse organization.
28 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system subdivision; adult segment; nervous system; adult mesothoracic segment; peripheral nervous system; sensillum; organ system; eo support cell; external compound sense organ; wing pouch.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Amyloidogenic glycoprotein, copper-binding; Amyloidogenic glycoprotein, extracellular; Amyloidogenic glycoprotein, extracellular domain conserved site; Amyloidogenic glycoprotein, heparin-binding; Amyloidogenic glycoprotein, intracellular domain, conserved site; Beta-amyloid precursor protein C-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.