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|Flybase description||The gene arrow is referred to in FlyBase by the symbol Dmel\arr (CG5912, FBgn0000119).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Wnt receptor activity; Wnt-protein binding.
There is experimental evidence that it is involved in the biological process: canonical Wnt receptor signaling pathway; nervous system development; regulation of compound eye pigmentation; Wnt receptor signaling pathway; protein targeting to lysosome; compound eye morphogenesis.
40 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; cuticle; organ system subdivision; non-connected developing system; presumptive embryonic/larval nervous system; multicellular structure; integumentary system; cuticular specialization; sensillum; external compound sense organ; midgut constriction; acellular anatomical structure; adult segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Epidermal growth factor-like; LDLR class B repeat; Low density lipoprotein receptor-related protein, 5/6; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Six-bladed beta-propeller, TolB-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.