Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name arr
Flybase description The gene arrow is referred to in FlyBase by the symbol Dmel\arr (CG5912, FBgn0000119).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -9.0267 -4.1731 -7.685567 -4.0924 -13.73289 -7.0848 -9.37977 -10.544567
    Affimetrix absolute value 5.237 5.573 5.246 6.394 4.995 5.743 5.335 4.913
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Wnt receptor activity; Wnt-protein binding.
There is experimental evidence that it is involved in the biological process: canonical Wnt receptor signaling pathway; nervous system development; regulation of compound eye pigmentation; Wnt receptor signaling pathway; protein targeting to lysosome; compound eye morphogenesis.
40 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; cuticle; organ system subdivision; non-connected developing system; presumptive embryonic/larval nervous system; multicellular structure; integumentary system; cuticular specialization; sensillum; external compound sense organ; midgut constriction; acellular anatomical structure; adult segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Epidermal growth factor-like; LDLR class B repeat; Low density lipoprotein receptor-related protein, 5/6; Low-density lipoprotein (LDL) receptor class A repeat; Low-density lipoprotein (LDL) receptor class A, conserved site; Six-bladed beta-propeller, TolB-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.