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|Flybase description||The gene absent, small, or homeotic discs 2 is referred to in FlyBase by the symbol Dmel\ash2 (CG6677, FBgn0000139).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding.
There is experimental evidence that it is involved in the biological process: histone H3-K4 methylation; imaginal disc-derived wing vein specification; chromatin-mediated maintenance of transcription; imaginal disc-derived wing morphogenesis.
30 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: adult segment; organ system subdivision; adult mesothoracic segment; thoracic segment; imaginal precursor; appendage segment; dorsal thoracic disc; antennal segment; mouthpart; multi-cell-component structure.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: B30.
2/SPRY domain; Concanavalin A-like lectin/glucanase; SPla/RYanodine receptor SPRY; SPla/RYanodine receptor subgroup; Zinc finger, FYVE/PHD-type; Zinc finger, PHD-type; Zinc finger, PHD-type, conserved site; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.