Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name asp
Flybase description The gene abnormal spindle is referred to in FlyBase by the symbol Dmel\asp (CG6875, FBgn0000140).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -24.9604 -12.6492 -17.132431 -17.2372 -23.772758 -20.2328 -25.81146 -19.402149
    Affimetrix absolute value 3.792 3.966 4.135 4.286 4.195 4.231 3.862 3.99
    Affymetric present call in "x" number of chips 0 0 0 0 0 1 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: microtubule binding; myosin light chain binding; protein kinase activity.
There is experimental evidence for 12 unique biological process terms, many of which group under: cellular component organization or biogenesis; cellular process involved in reproduction; multicellular organismal reproductive process; cell cycle; anatomical structure development; cell cycle process; organelle organization; localization; kinetochore organization; cell division.
23 alleles are reported.
The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; cytoplasmic part; multicellular structure; female germline cyst; organelle; organ system subdivision; intracellular organelle part; germarium; sensillum; cell cycle; spermatocyte; imaginal precursor; external compound sense organ; adult segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Calponin homology domain; IQ motif, EF-hand binding site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.