Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ben
Flybase description The gene bendless is referred to in FlyBase by the symbol Dmel\ben (CG18319, FBgn0000173).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.2356 2.2881 1.417946 1.8947 -0.451644 1.2972 1.70246 1.50595
    Affimetrix absolute value 9.541 8.785 8.669 9.3 8.604 8.933 9.311 8.784
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ubiquitin-protein ligase activity.
There is experimental evidence that it is involved in the biological process: jump response; response to anesthetic; flight behavior; axonogenesis; axon target recognition; photoreceptor cell morphogenesis; grooming behavior.
25 alleles are reported.
The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system subdivision; external compound sense organ; peripheral nervous system; adult segment; nervous system; adult mesothoracic segment; multi-cell-component structure; indirect flight muscle; synaptic neuropil subdomain; rhabdomere R7.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Ubiquitin-conjugating enzyme, E2; Ubiquitin-conjugating enzyme, active site; Ubiquitin-conjugating enzyme/RWD-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.