Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name bib
Flybase description The gene big brain is referred to in FlyBase by the symbol Dmel\bib (CG4722, FBgn0000180).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -74.139 -36.4952 -51.742409 -52.4443 -68.658623 -42.5939 -79.04894 -59.346107
    Affimetrix absolute value 2.216 2.433 2.5 2.675 2.692 3.174 2.247 2.396
    Affymetric present call in "x" number of chips 0 1 1 1 0 3 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cation channel activity.
There is experimental evidence that it is involved in the biological process: endosomal lumen acidification; lateral inhibition; endosome organization; cell-cell adhesion; mesoderm development.
29 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; non-connected developing system; portion of tissue; somatic cell; multicellular structure; sense organ; sensillum; organ system subdivision; presumptive embryonic/larval nervous system; nervous system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Aquaporin; Aquaporin-like; Major intrinsic protein; Major intrinsic protein, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.