Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name BicD
Flybase description The gene Bicaudal D is referred to in FlyBase by the symbol Dmel\BicD (CG6605, FBgn0000183).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.3954 0.5004 -0.45094 -1.4933 -2.591419 -2.0162 -1.62544 -1.890346
    Affimetrix absolute value 6.667 7.794 8.035 7.822 7.394 7.552 7.877 7.392
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: oocyte microtubule cytoskeleton polarization; intracellular mRNA localization; germarium-derived oocyte fate determination; oogenesis; mRNA transport; RNA transport; germarium-derived egg chamber formation.
64 alleles are reported.
The phenotypes of these alleles are annotated with 27 unique terms, many of which group under: organ system; female germline cyst; egg; hemocyte; organ system subdivision; somatic cell; multicellular structure; somatic stem cell; germarium; nuclear part; embryonic/larval hemocoel; embryonic head; blastoderm embryo; presumptive embryonic/larval nervous system; embryonic thorax; cytoplasmic part; external compound sense organ.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Bicaudal-D protein, microtubule-associated.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.