Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name btd
Flybase description The gene buttonhead is referred to in FlyBase by the symbol Dmel\btd (CG12653, FBgn0000233).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -46.0092 -25.3363 -40.923647 -44.4401 -70.082837 -54.0035 -47.33129 -49.031354
    Affimetrix absolute value 2.901 2.975 2.86 2.914 2.656 2.808 2.989 2.661
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transcription factor binding.
There is experimental evidence that it is involved in the biological process: positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; cephalic furrow formation; head segmentation.
27 alleles are reported.
The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: organ system subdivision; antennal segment; abdominal lateral pentascolopidial chordotonal organ lch5; adult segment; larval head segment; embryonic segment; organ system; external compound sense organ; portion of tissue; embryonic head; sensillum; larval abdominal segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.