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|Flybase description||The gene cactus is referred to in FlyBase by the symbol Dmel\cact (CG5848, FBgn0000250).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: antifungal humoral response; nervous system development; dorsal/ventral axis specification; oogenesis; antimicrobial humoral response; positive regulation of antifungal peptide biosynthetic process; response to DNA damage stimulus; dorsal appendage formation; phagocytosis, engulfment.
131 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system; embryonic/larval hemocoel; portion of tissue; hemocyte; non-connected developing system; multicellular structure; cuticle; egg; podocyte; spiracle.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages.