Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name cad
Flybase description The gene caudal is referred to in FlyBase by the symbol Dmel\cad (CG1759, FBgn0000251).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.199 -17.0002 -22.778096 -5.6154 -0.201209 2.9138 -3.42239 -0.659086
    Affimetrix absolute value 5.091 3.625 3.858 5.902 8.893 10.103 6.925 7.953
    Affymetric present call in "x" number of chips 3 0 0 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: gastrulation involving germ band extension; hindgut morphogenesis; segment specification; genital disc development; genital disc anterior/posterior pattern formation; germ-band extension.
31 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: multicellular structure; organ system; anatomical structure; abdominal segment 8; portion of tissue; adult; abdominal segment 10; embryonic head; sensillum; embryonic abdomen; organ system subdivision; late extended germ band embryo.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Helix-turn-helix motif, lambda-like repressor; Homeobox; Homeobox, conserved site; Homeobox, eukaryotic; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.