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|Flybase description||The gene crinkled is referred to in FlyBase by the symbol Dmel\ck (CG7595, FBgn0000317).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: actin-dependent ATPase activity; myosin light chain binding; ATP binding.
There is experimental evidence that it is involved in the biological process: antennal morphogenesis; imaginal disc-derived wing vein morphogenesis; bristle morphogenesis; antennal development; sensory organ development; actin filament-based movement; imaginal disc-derived wing hair organization; sensory perception of sound.
37 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; wing; ocellar bristle; microchaeta; arista; macrochaeta; wing hair.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Band 4.
1 domain; FERM central domain; FERM domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; IQ motif, EF-hand binding site; MyTH4 domain; Myosin head, motor domain; Pleckstrin homology-type; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages.