Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ck
Flybase description The gene crinkled is referred to in FlyBase by the symbol Dmel\ck (CG7595, FBgn0000317).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.8714 -1.7108 -2.181737 1.2909 -7.388091 -2.3087 -1.37188 -4.636437
    Affimetrix absolute value 6.456 6.877 7.152 8.749 6.004 7.371 8.138 6.249
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: actin-dependent ATPase activity; myosin light chain binding; ATP binding.
There is experimental evidence that it is involved in the biological process: antennal morphogenesis; imaginal disc-derived wing vein morphogenesis; bristle morphogenesis; antennal development; sensory organ development; actin filament-based movement; imaginal disc-derived wing hair organization; sensory perception of sound.
37 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; wing; ocellar bristle; microchaeta; arista; macrochaeta; wing hair.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Band 4.
1 domain; FERM central domain; FERM domain; FERM, N-terminal; FERM/acyl-CoA-binding protein, 3-helical bundle; IQ motif, EF-hand binding site; MyTH4 domain; Myosin head, motor domain; Pleckstrin homology-type; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages.