Flygut: an atlas of the Drosophila adult midgut

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Gene name Chc
Flybase description The gene Clathrin heavy chain is referred to in FlyBase by the symbol Dmel\Chc (CG9012, FBgn0000319).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.7751 6.7508 3.125341 3.5032 1.632802 2.793 4.98335 2.491365
    Affimetrix absolute value 9.232 10.364 9.757 10.178 9.416 10.04 10.844 9.476
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding; structural molecule activity.
There is experimental evidence that it is involved in the biological process: sperm individualization; positive regulation of Notch signaling pathway; dsRNA transport; endocytosis; positive regulation of endocytosis; liquid clearance, open tracheal system; regulation of tube length, open tracheal system; regulation of growth; extracellular matrix organization; compound eye retinal cell programmed cell death.
25 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: cytoplasmic part; organ system; organelle; external compound sense organ; nervous system; organ system subdivision; intracellular membrane-bounded organelle; synapse; peripheral nervous system; non-connected developing system; imaginal precursor; spermatozoon; garland cell.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Armadillo-type fold; Clathrin, heavy chain; Clathrin, heavy chain, linker, core motif; Clathrin, heavy chain, linker/propeller domain; Clathrin, heavy chain, propeller repeat; Clathrin, heavy chain, propeller, N-terminal; Clathrin, heavy chain/VPS, 7-fold repeat; Tetratricopeptide-like helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.