Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name crn
Flybase description The gene crooked neck is referred to in FlyBase by the symbol Dmel\crn (CG3193, FBgn0000377).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.9368 -2.8778 -3.15038 -3.4388 -3.660441 -3.8993 -3.31868 -3.856465
    Affimetrix absolute value 6.436 6.098 6.529 6.63 6.891 6.634 6.848 6.305
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: binding.
There is experimental evidence that it is involved in the biological process: oenocyte development; Malpighian tubule morphogenesis; glial cell migration; axon ensheathment; regulation of alternative nuclear mRNA splicing, via spliceosome; neurogenesis.
44 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval oenocyte precursor; Malpighian tubule; glial cell; embryonic/larval glial cell; embryonic Malpighian tubule; peripheral glial cell; embryo.
It has one annotated transcript and one annotated polypeptide.
Protein features are: RNA-processing protein, HAT helix; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.