Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name csw
Flybase description The gene corkscrew is referred to in FlyBase by the symbol Dmel\csw (CG3954, FBgn0000382).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.4387 -2.14 -4.317118 -4.0413 -7.448083 -5.2617 -2.24739 -5.027932
    Affimetrix absolute value 7.131 6.583 6.072 6.401 5.874 6.169 7.412 5.954
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein tyrosine phosphatase activity; protein binding.
There is experimental evidence for 14 unique biological process terms, many of which group under: anatomical structure development; biological regulation; signaling; regulation of biological process; transmembrane receptor protein tyrosine kinase signaling pathway; cellular process involved in reproduction; macromolecule modification; open tracheal system development; cell cycle; organ development; anterior/posterior axis specification.
57 alleles are reported.
The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; adult mesothoracic segment; peripheral nervous system; primordium; germ layer; nervous system; eo support cell; hypodermal muscle of larval abdomen; cell cycle; imaginal precursor; ectoderm derivative; antennal segment.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase, receptor/non-receptor type; Protein-tyrosine/Dual-specificity phosphatase; SH2 motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed during early pupal stages.