Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name CycA
Flybase description The gene Cyclin A is referred to in FlyBase by the symbol Dmel\CycA (CG5940, FBgn0000404).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.4477 -6.5421 -6.652759 -5.9066 -6.88433 -3.9658 -16.5866 -7.180005
    Affimetrix absolute value 4.931 4.914 5.452 5.846 5.996 6.614 4.516 5.416
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; cyclin-dependent protein kinase regulator activity.
There is experimental evidence that it is involved in the biological process: mitosis; regulation of exit from mitosis; regulation of mitosis; asymmetric neuroblast division; syncytial blastoderm mitotic cell cycle; regulation of mitotic cell cycle, embryonic; lateral inhibition; cellular process; mitotic sister chromatid segregation; neurogenesis.
100 alleles are reported.
The phenotypes of these alleles are annotated with 36 unique terms, many of which group under: organ system subdivision; organ system; embryonic/larval neuron; nervous system; ventral nerve cord primordium; germarium; cell cycle; external compound sense organ; female germline cyst; primordium.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Cyclin A, G2/mitotic-specific; Cyclin A/B/D/E; Cyclin, C-terminal; Cyclin, N-terminal; Cyclin-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.