Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name D
Flybase description The gene Dichaete is referred to in FlyBase by the symbol Dmel\D (CG5893, FBgn0000411).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -14.6355 -18.0127 -29.743679 -33.9923 -41.459926 -41.1984 -28.52931 -30.532151
    Affimetrix absolute value 4.538 3.469 3.293 3.316 3.388 3.198 3.814 3.367
    Affymetric present call in "x" number of chips 3 1 0 0 0 0 1 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: DNA bending activity; sequence-specific DNA binding transcription factor activity; transcription factor binding; sequence-specific DNA binding; DNA binding; mRNA 3'-UTR binding.
There is experimental evidence for 11 unique biological process terms, many of which group under: multicellular organismal process; anatomical structure development; biological regulation; regulation of cellular macromolecule biosynthetic process; developmental process; central nervous system development; regulation of metabolic process; regionalization; instar larval development; system development; dorsal/ventral axis specification; localization.
64 alleles are reported.
The phenotypes of these alleles are annotated with 64 unique terms, many of which group under: organ system subdivision; adult segment; abdominal ventral denticle belt; antennal segment; ventral nerve cord primordium; adult mesothoracic segment; embryonic/larval neuron; external compound sense organ; commissure; primordium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: High mobility group, HMG1/HMG2; High mobility group, superfamily.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.