Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Dfd
Flybase description The gene Deformed is referred to in FlyBase by the symbol Dmel\Dfd (CG2189, FBgn0000439).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -56.154 -32.8085 -45.212661 -55.0307 -72.945008 -72.4313 -53.57834 -43.927273
    Affimetrix absolute value 2.598 2.587 2.717 2.617 2.581 2.392 2.814 2.822
    Affymetric present call in "x" number of chips 0 0 1 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: embryonic morphogenesis; embryo development; brain development; induction of apoptosis.
43 alleles are reported.
The phenotypes of these alleles are annotated with 36 unique terms, many of which group under: organ system subdivision; embryonic segment; thoracic segment; cephalopharyngeal skeleton; organ system; external compound sense organ; larval head segment; antennal segment; mouthpart; late extended germ band embryo.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeobox; Homeobox protein, antennapedia type; Homeobox protein, antennapedia type, conserved site; Homeobox, conserved site; Homeobox, eukaryotic; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages.