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|Flybase description||The gene cGMP-dependent protein kinase 21D is referred to in FlyBase by the symbol Dmel\Pkg21D (CG3324, FBgn0000442).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cGMP-dependent protein kinase activity.
There is experimental evidence that it is involved in the biological process: protein phosphorylation.
8 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: AGC-kinase, C-terminal; Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; RmlC-like jelly roll fold; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain; cGMP-dependent kinase; cGMP-dependent protein kinase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages.