Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Hr46
Flybase description The gene Hormone receptor-like in 46 is referred to in FlyBase by the symbol Dmel\Hr46 (CG33183, FBgn0000448).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -67.6446 -40.6583 -52.378302 -65.5334 -86.391185 -76.0533 -78.05902 -57.884494
    Affimetrix absolute value 2.341 2.286 2.474 2.363 2.335 2.314 2.27 2.423
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; ligand-dependent nuclear receptor activity.
There is experimental evidence that it is involved in the biological process: mushroom body development.
64 alleles are reported.
The phenotypes of these alleles are annotated with: taenidial fold; mushroom body; presumptive embryonic/larval peripheral nervous system; trichogen cell; wing; adult head; puparium.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Nuclear hormone receptor, ligand-binding; Nuclear hormone receptor, ligand-binding, core; Steroid hormone receptor; Thyroid hormone receptor; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 12-18 embryonic stages.