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|Flybase description||The gene disembodied is referred to in FlyBase by the symbol Dmel\dib (CG12028, FBgn0000449).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: ecdysteroid 22-hydroxylase activity.
There is experimental evidence that it is involved in the biological process: central nervous system development; dorsal closure; ecdysone biosynthetic process; head involution; midgut development; chitin-based embryonic cuticle biosynthetic process.
24 alleles are reported.
The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: organ system; multicellular structure; cuticle; organ system subdivision; nervous system; primordium; non-connected developing system; integumentary system; cuticular specialization; multi-cell-component structure.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 00-06 hour embryonic stages.