Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name disco
Flybase description The gene disconnected is referred to in FlyBase by the symbol Dmel\disco (CG9908, FBgn0000459).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -9.9845 -17.7194 -29.72838 -21.9416 -43.477707 -25.8278 -23.6092 -27.491743
    Affimetrix absolute value 5.103 3.512 3.287 3.94 3.322 3.876 3.992 3.52
    Affymetric present call in "x" number of chips 3 3 1 3 1 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: DNA binding.
There is experimental evidence that it is involved in the biological process: brain development; eclosion rhythm; locomotor rhythm; positive regulation of transcription from RNA polymerase II promoter.
25 alleles are reported.
The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: organ system subdivision; organ system; nervous system; external compound sense organ; adult segment; cuticle; presumptive embryonic/larval nervous system; cephalopharyngeal skeleton; multi-cell-component structure; peripheral nervous system.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.