Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Dl
Flybase description The gene Delta is referred to in FlyBase by the symbol Dmel\Dl (CG3619, FBgn0000463).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -18.7529 -6.769 -6.79741 -9.307 -9.305327 -5.6389 -5.12973 -9.113788
    Affimetrix absolute value 4.181 4.86 5.435 5.231 5.615 6.11 6.21 5.068
    Affymetric present call in "x" number of chips 2 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Notch binding.
There is experimental evidence for 26 unique biological process terms, many of which group under: anatomical structure development; biological regulation; multicellular organismal reproductive process; cellular process involved in reproduction; post-embryonic appendage morphogenesis; post-embryonic organ morphogenesis; cellular component organization or biogenesis; sensory organ development; leg morphogenesis; localization.
449 alleles are reported.
The phenotypes of these alleles are annotated with 110 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; nervous system; peripheral nervous system; primordium; embryonic/larval neuron; female germline cyst; adult mesothoracic segment; ectoderm derivative.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Delta/Serrate/lag-2 (DSL) protein; EGF; EGF calcium-binding; EGF-like calcium-binding; EGF-like calcium-binding, conserved site; EGF-like region, conserved site; EGF-type aspartate/asparagine hydroxylation site; Epidermal growth factor-like; Epidermal growth factor-like, type 3; Notch ligand, N-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.