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|Flybase description||The gene Leukocyte-antigen-related-like is referred to in FlyBase by the symbol Dmel\Lar (CG10443, FBgn0000464).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein tyrosine phosphatase activity; SAM domain binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; locomotion; multicellular organismal reproductive process; macromolecule modification; biological regulation; taxis; compound eye photoreceptor development; cell adhesion; protein modification process; regulation of developmental process; cell projection organization; multicellular organism reproduction.
57 alleles are reported.
The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: organ system subdivision; female germline cyst; embryonic/larval neuron; organ system; germarium; multi-cell-component structure; peripheral nervous system; egg; adult segment; nervous system.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase, receptor/non-receptor type; Protein-tyrosine/Dual-specificity phosphatase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 12-24 hour embryonic stages, at stages throughout the pupal period.