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|Flybase description||The gene Drop is referred to in FlyBase by the symbol Dmel\Dr (CG1897, FBgn0000492).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; DNA binding.
There is experimental evidence that it is involved in the biological process: glial cell development; dorsal/ventral pattern formation, imaginal disc; wing and notum subfield formation; imaginal disc-derived male genitalia development; brain development; imaginal disc-derived wing morphogenesis; regulation of cell fate specification; wing disc pattern formation.
57 alleles are reported.
The phenotypes of these alleles are annotated with 168 unique terms, many of which group under: hypodermal muscle of larval abdomen; organ system; A1-7 oblique muscle; A1-7 transverse muscle; larval abdominal segment 5; hypodermal muscle of metathorax; organ system subdivision; thoracic segment; hypodermal muscle of mesothorax; A1-7 ventral acute muscle 2.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeobox; Homeobox, conserved site; Homeobox, eukaryotic; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.