Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name dsx
Flybase description The gene doublesex is referred to in FlyBase by the symbol Dmel\dsx (CG11094, FBgn0000504).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.4918 -2.8546 -3.401117 -5.2151 -6.160142 -4.5896 -6.74492 -5.018265
    Affimetrix absolute value 8.218 6.116 6.458 6.007 6.168 6.364 5.843 6.027
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; protein homodimerization activity.
There is experimental evidence that it is involved in the biological process: imaginal disc-derived female genitalia development; imaginal disc-derived male genitalia development; genital disc development; axon midline choice point recognition.
128 alleles are reported.
The phenotypes of these alleles are annotated with 31 unique terms, many of which group under: organ system subdivision; organ system; adult segment; gland; imaginal precursor; portion of tissue; hub cell; larval abdominal segment 8; nervous system; external compound sense organ; female germline cyst.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: DM DNA-binding; Doublesex dimerisation.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed during early pupal stages, in adult male stages.