Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name ems
Flybase description The gene empty spiracles is referred to in FlyBase by the symbol Dmel\ems (CG2988, FBgn0000576).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -55.2558 -29.8627 -43.866485 -44.7724 -65.53815 -62.8782 -59.23374 -50.247626
    Affimetrix absolute value 2.633 2.728 2.752 2.934 2.729 2.591 2.667 2.637
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: spiracle morphogenesis, open tracheal system; dendrite morphogenesis; embryonic development via the syncytial blastoderm; brain development; axonogenesis; neuroblast development; brain segmentation; open tracheal system development; ventral cord development.
18 alleles are reported.
The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: organ system subdivision; nervous system; cephalopharyngeal skeleton; organ system; late extended germ band embryo; antennal segment; larval head segment; multi-cell-component structure; presumptive embryonic/larval nervous system; primordium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.