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|Flybase description||The gene empty spiracles is referred to in FlyBase by the symbol Dmel\ems (CG2988, FBgn0000576).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: spiracle morphogenesis, open tracheal system; dendrite morphogenesis; embryonic development via the syncytial blastoderm; brain development; axonogenesis; neuroblast development; brain segmentation; open tracheal system development; ventral cord development.
18 alleles are reported.
The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: organ system subdivision; nervous system; cephalopharyngeal skeleton; organ system; late extended germ band embryo; antennal segment; larval head segment; multi-cell-component structure; presumptive embryonic/larval nervous system; primordium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.