Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name exd
Flybase description The gene extradenticle is referred to in FlyBase by the symbol Dmel\exd (CG8933, FBgn0000611).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.4451 2.3204 1.61584 1.7229 -1.228321 1.2372 1.99181 0.53536
    Affimetrix absolute value 8.911 8.819 8.86 9.162 8.47 8.868 9.524 8.473
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; sequence-specific DNA binding; sequence-specific enhancer binding RNA polymerase II transcription factor activity; DNA binding.
There is experimental evidence that it is involved in the biological process: oenocyte development; brain development.
63 alleles are reported.
The phenotypes of these alleles are annotated with 55 unique terms, many of which group under: organ system subdivision; adult segment; organ system; cephalopharyngeal skeleton; thoracic segment; antennal segment; presumptive embryonic/larval nervous system; appendage segment; multi-cell-component structure; pharyngeal sclerite.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; PBX.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages.