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|Flybase description||The gene Enhancer of zeste is referred to in FlyBase by the symbol Dmel\E(z) (CG6502, FBgn0000629).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: histone methyltransferase activity (H3-K27 specific); protein binding; histone methyltransferase activity (H3-K9 specific); histone methyltransferase activity.
There is experimental evidence that it is involved in the biological process: histone methylation; axon guidance; histone H3-K27 methylation; cuticle hydrocarbon biosynthetic process; dendrite morphogenesis; histone H3-K9 methylation; muscle organ development; syncytial blastoderm mitotic cell cycle; neurogenesis.
115 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: adult segment; organ system subdivision; thoracic segment; imaginal precursor; dorsal thoracic disc; female germline cyst; larval thorax; adult abdominal segment; somatic cell; egg; embryonic/larval imaginal precursor; cell cycle; adult metathoracic segment; adult mesothoracic segment; adult external prothorax.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: SANT domain, DNA binding; SET domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.