Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name E(z)
Flybase description The gene Enhancer of zeste is referred to in FlyBase by the symbol Dmel\E(z) (CG6502, FBgn0000629).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.4299 -3.5707 -5.086473 -4.9765 -7.703158 -5.998 -5.36551 -6.850512
    Affimetrix absolute value 5.984 5.785 5.876 6.095 5.852 5.987 6.163 5.487
    Affymetric present call in "x" number of chips 2 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: histone methyltransferase activity (H3-K27 specific); protein binding; histone methyltransferase activity (H3-K9 specific); histone methyltransferase activity.
There is experimental evidence that it is involved in the biological process: histone methylation; axon guidance; histone H3-K27 methylation; cuticle hydrocarbon biosynthetic process; dendrite morphogenesis; histone H3-K9 methylation; muscle organ development; syncytial blastoderm mitotic cell cycle; neurogenesis.
115 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: adult segment; organ system subdivision; thoracic segment; imaginal precursor; dorsal thoracic disc; female germline cyst; larval thorax; adult abdominal segment; somatic cell; egg; embryonic/larval imaginal precursor; cell cycle; adult metathoracic segment; adult mesothoracic segment; adult external prothorax.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: SANT domain, DNA binding; SET domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.