Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Fas2
Flybase description The gene Fasciclin 2 is referred to in FlyBase by the symbol Dmel\Fas2 (CG3665, FBgn0000635).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.4589 -2.5167 -8.853432 -5.7953 -12.729078 -4.5744 -4.01688 -10.007108
    Affimetrix absolute value 5.552 6.296 5.134 5.889 5.14 6.378 6.546 5.013
    Affymetric present call in "x" number of chips 3 3 2 3 2 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 14 unique biological process terms, many of which group under: anatomical structure development; biological regulation; cellular component organization or biogenesis; neuron differentiation; regulation of developmental process; regulation of anatomical structure size; learning or memory; sensory organ development; homophilic cell adhesion; open tracheal system development; central nervous system development; organ morphogenesis; imaginal disc-derived male genitalia development; regulation of multicellular organismal development; regulation of epidermal growth factor receptor signaling pathway.
73 alleles are reported.
The phenotypes of these alleles are annotated with 49 unique terms, many of which group under: organ system subdivision; multi-cell-component structure; sensillum; adult segment; embryonic/larval neuron; peripheral nervous system; external compound sense organ; nervous system; synapse; integumentary plate; late extended germ band embryo.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Neural cell adhesion.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 06-24 hour embryonic stages, at stages throughout the pupal period.