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|Flybase description||The gene flightless I is referred to in FlyBase by the symbol Dmel\fliI (CG1484, FBgn0000709).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: calcium ion binding; actin binding.
There is experimental evidence that it is involved in the biological process: adult somatic muscle development; myofibril assembly; gastrulation involving germ band extension; flight behavior.
30 alleles are reported.
The phenotypes of these alleles are annotated with: Z disc; striated muscle thin filament; striated muscle myosin thick filament; myofibril; presumptive embryonic/larval peripheral nervous system; sarcomere; presumptive embryonic/larval central nervous system; blastoderm embryo; indirect flight muscle; muscle cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Gelsolin; Gelsolin domain; Leucine-rich repeat; Leucine-rich repeat, typical subtype.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.