Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name fliI
Flybase description The gene flightless I is referred to in FlyBase by the symbol Dmel\fliI (CG1484, FBgn0000709).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.9108 -0.3928 -1.341459 0.3743 -2.361524 -1.6482 -3.22285 -2.042351
    Affimetrix absolute value 6.441 7.538 7.768 8.436 7.533 7.859 6.915 7.298
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: calcium ion binding; actin binding.
There is experimental evidence that it is involved in the biological process: adult somatic muscle development; myofibril assembly; gastrulation involving germ band extension; flight behavior.
30 alleles are reported.
The phenotypes of these alleles are annotated with: Z disc; striated muscle thin filament; striated muscle myosin thick filament; myofibril; presumptive embryonic/larval peripheral nervous system; sarcomere; presumptive embryonic/larval central nervous system; blastoderm embryo; indirect flight muscle; muscle cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Gelsolin; Gelsolin domain; Leucine-rich repeat; Leucine-rich repeat, typical subtype.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.