Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name dup
Flybase description The gene double parked is referred to in FlyBase by the symbol Dmel\dup (CG8171, FBgn0000996).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -18.0624 -7.7096 -7.787473 -9.9565 -12.645031 -9.3048 -17.06068 -10.912134
    Affimetrix absolute value 4.243 4.674 5.264 5.074 5.113 5.369 4.466 4.834
    Affymetric present call in "x" number of chips 1 3 3 3 2 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: DNA binding.
There is experimental evidence that it is involved in the biological process: chorion-containing eggshell formation; DNA replication checkpoint; mitotic sister chromatid separation; cytokinesis; DNA replication; antimicrobial humoral response; centrosome duplication; DNA endoreduplication.
20 alleles are reported.
The phenotypes of these alleles are annotated with: eye disc; mitotic cell cycle; metaphase plate; follicle cell; imaginal disc; S phase; cycle 16 embryo; mitotic metaphase.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DNA replication factor CDT1-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.