Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name G-salpha60A
Flybase description The gene G protein sα 60A is referred to in FlyBase by the symbol Dmel\G-sα60A (CG2835, FBgn0001123).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.8073 2.2415 -0.235431 1.7898 -1.672582 1.2968 1.91342 0.28424
    Affimetrix absolute value 9.883 8.776 8.275 9.219 8.086 8.936 9.462 8.222
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity.
There is experimental evidence that it is involved in the biological process: bristle development; synaptic transmission; wing disc development; response to trehalose stimulus; sensory perception of sweet taste; neuromuscular junction development; imaginal disc-derived wing morphogenesis.
24 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system subdivision; organ system; adult segment; nervous system; adult mesothoracic segment; mouthpart; somatic cell; gustatory sensory organ; synapse; integumentary specialisation; embryonic/larval fat body; integumentary plate.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: G protein alpha subunit, helical insertion; G-protein alpha subunit, group S; Guanine nucleotide binding protein (G-protein), alpha subunit.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.