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|Flybase description||The gene gurken is referred to in FlyBase by the symbol Dmel\grk (CG17610, FBgn0001137).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: gurken receptor binding; epidermal growth factor receptor binding.
There is experimental evidence that it is involved in the biological process: maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded; establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification; oocyte microtubule cytoskeleton organization; border follicle cell migration; chorion-containing eggshell pattern formation.
80 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: egg; organ system; female germline cyst; adult segment; chorion; organ system subdivision; adult mesothoracic segment; portion of tissue; epithelial furrow; cell part.
It has one annotated transcript and one annotated polypeptide.
Protein features are: EGF-like region, conserved site; Epidermal growth factor-like; Epidermal growth factor-like, type 3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed during late pupal stages.