Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Gs1
Flybase description The gene Glutamine synthetase 1 is referred to in FlyBase by the symbol Dmel\Gs1 (CG2718, FBgn0001142).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 4.7747 2.2327 -1.860242 4.8509 -1.237189 -1.3116 -5.55864 1.550917
    Affimetrix absolute value 10.655 8.759 7.334 10.65 8.473 8.186 6.122 8.824
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: glutamate-ammonia ligase activity.
There is experimental evidence that it is involved in the biological process: glutamine metabolic process; mitochondrion organization.
16 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic somatic muscle; A1-7 dorsal oblique muscle 2; muscle attachment site.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Glutamine synthetase, beta-Grasp; Glutamine synthetase, catalytic domain; Glutamine synthetase/guanido kinase, catalytic domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages.