Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name H
Flybase description The gene Hairless is referred to in FlyBase by the symbol Dmel\H (CG5460, FBgn0001169).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -14.655 -4.894 -9.097311 -11.9299 -16.763963 -11.0587 -12.13484 -17.941826
    Affimetrix absolute value 4.546 5.332 5.039 4.838 4.723 5.102 4.961 4.171
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transcription corepressor activity.
There is experimental evidence that it is involved in the biological process: negative regulation of Notch signaling pathway; sensory organ boundary specification; regulation of cell death; sensory organ precursor cell fate determination; imaginal disc-derived wing margin morphogenesis; lateral inhibition; imaginal disc-derived wing vein morphogenesis; wing disc dorsal/ventral pattern formation.
125 alleles are reported.
The phenotypes of these alleles are annotated with 56 unique terms, many of which group under: organ system subdivision; adult segment; adult mesothoracic segment; sensillum; eo support cell; external compound sense organ; peripheral nervous system; nervous system; tormogen cell; primordium.
It has 4 annotated transcripts and 4 annotated polypeptides.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.