Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Hn
Flybase description The gene Henna is referred to in FlyBase by the symbol Dmel\Hn (CG7399, FBgn0001208).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.4055 -11.633 -20.136581 -24.2413 -30.486983 -21.9723 -3.00449 -13.882867
    Affimetrix absolute value 5.731 4.094 3.882 3.809 3.829 4.113 7.193 4.483
    Affymetric present call in "x" number of chips 2 0 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: phenylalanine 4-monooxygenase activity.
There is experimental evidence that it is involved in the biological process: L-phenylalanine catabolic process; eye pigment biosynthetic process; phagocytosis, engulfment.
20 alleles are reported.
The phenotypes of these alleles are annotated with: eye; pigment cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Aromatic amino acid hydroxylase; Aromatic amino acid hydroxylase, C-terminal; Aromatic amino acid hydroxylase, iron/copper binding site; Phenylalanine-4-hydroxylase, tetrameric form; Tyrosine 3-monooxygenase-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed at stages throughout the larval period, during late pupal stages, in adult male stages.