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|Flybase description||The gene homothorax is referred to in FlyBase by the symbol Dmel\hth (CG17117, FBgn0001235).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific enhancer binding RNA polymerase II transcription factor activity; DNA binding.
There is experimental evidence that it is involved in the biological process: positive regulation of transcription from RNA polymerase II promoter; compound eye development; specification of segmental identity, antennal segment; specification of segmental identity, head; segmentation; compound eye photoreceptor fate commitment; brain development; imaginal disc-derived wing morphogenesis; haltere morphogenesis; imaginal disc-derived leg morphogenesis.
70 alleles are reported.
The phenotypes of these alleles are annotated with 64 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; abdominal lateral pentascolopidial chordotonal organ lch5; thoracic segment; embryonic segment; antennal segment; appendage segment; cuticle; adult mesothoracic segment.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: Homeobox; Homeobox KN domain; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.