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|Flybase description||The gene invected is referred to in FlyBase by the symbol Dmel\inv (CG17835, FBgn0001269).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: sequence-specific DNA binding transcription factor activity; transcription regulatory region sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: neuroblast fate determination; compartment pattern formation.
37 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; organ system subdivision; adult segment; adult mesothoracic segment; thoracic segment; non-connected developing system; embryonic hindgut; cuticle; multi-cell-component structure; nervous system; adult; developing material anatomical entity.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Helix-turn-helix motif, lambda-like repressor; Homeobox; Homeobox engrailed; Homeobox engrailed, C-terminal; Homeobox engrailed-type, conserved site; Homeobox, conserved site; Homeobox, eukaryotic; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages.