Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Jra
Flybase description The gene Jun-related antigen is referred to in FlyBase by the symbol Dmel\Jra (CG2275, FBgn0001291).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.2878 1.5855 -0.423993 -0.329 -1.353094 -0.2682 -1.65343 -0.406953
    Affimetrix absolute value 8.35 8.274 8.068 8.383 8.335 8.624 7.854 8.146
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: negative regulation of antimicrobial humoral response; micropyle formation; JNK cascade; synaptic growth at neuromuscular junction; imaginal disc fusion, thorax closure; dorsal appendage formation; phagocytosis, engulfment.
28 alleles are reported.
The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; nervous system; imaginal precursor; rhabdomere; primordium; commissure; cell projection; ommatidial precursor cluster; adult segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Basic-leucine zipper (bZIP) transcription factor; Eukaryotic transcription factor, Skn-1-like, DNA-binding; Jun-like transcription factor; Transcription factor Jun; bZIP transcription factor, bZIP-1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 18-24 hour embryonic stages, during early pupal stages.