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|Flybase description||The gene knirps is referred to in FlyBase by the symbol Dmel\kni (CG4717, FBgn0001320).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: dendrite morphogenesis; regulation of mitosis; muscle organ development; epidermis development.
108 alleles are reported.
The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: embryonic abdomen; embryonic segment; multicellular structure; adult segment; organ system; organ system subdivision; abdominal segment 7; thoracic segment; late extended germ band embryo; embryonic abdominal segment 4; dorsal trunk primordium; dorsal branch primordium; embryonic/larval hemocoel.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Nuclear hormone receptor, ligand-binding; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages.