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|Flybase description||The gene kohtalo is referred to in FlyBase by the symbol Dmel\kto (CG8491, FBgn0001324).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; RNA polymerase II transcription cofactor activity.
There is experimental evidence that it is involved in the biological process: bristle development; positive regulation of Wnt receptor signaling pathway; compound eye development; sex comb development; regulation of transcription from RNA polymerase II promoter; leg segmentation.
22 alleles are reported.
The phenotypes of these alleles are annotated with: wing margin; eye disc; trichogen cell; antennal disc; photoreceptor cell; heart primordium; mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Mediator complex, subunit Med12; Mediator complex, subunit Med12, LCEWAV-domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.