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|Flybase description||The gene Helicase is referred to in FlyBase by the symbol Dmel\Hlc (CG1666, FBgn0001565).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATP-dependent RNA helicase activity.
There is experimental evidence that it is involved in the biological process: neurogenesis.
21 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; central nervous system; peripheral nervous system; mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DEAD-like helicase; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; RNA helicase, DEAD-box type, Q motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages, in adult female stages.